Evidence-based practice in clinical management is grounded primarily in:

Evidence-based practice in clinical management is fundamentally based on systematically reviewed evidence, which synthesizes research findings to provide comprehensive insights into clinical questions. Systematic reviews are considered the highest level of evidence, as they compile and critically evaluate multiple studies to assess the effectiveness and safety of interventions. These reviews follow rigorous methodologies, ensuring that the data gathered is reliable and applicable to real-world clinical scenarios.

This approach emphasizes the importance of not only collecting data but also analyzing it in a way that allows for evidence-based decision-making. The results from systematic reviews can guide clinical practice guidelines and inform best practices, ensuring that healthcare providers can offer care that is both effective and grounded in the most reliable evidence available.

While clinical practice guidelines do play an important role in translating systematic review findings into practice, they are ultimately based on the highest-quality evidence synthesized from systematic reviews. Therefore, systematic reviews form the foundation upon which clinical recommendations are built in evidence-based practice.